Programme

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Content

The content of the FEMS Summer School for Postdocs (#FSSfP) will be focused on the following theme:

Microbial Evolvability Mechanisms: Resistance, Biology, and Strategies to Defeat and Detect

Programme

Bacteria and phages led the discovery of nearly all basic molecular biological processes for all of life.  More recently, microbes are the vanguard of intriguing new molecular mechanisms that drive evolution and the ability to evolve.  Evolution by variation and selection includes mechanisms of inheritance and creation of variation. These mechanisms, from stress-induced mutagenesis, to RNA- and protein-mediated inheritance, to persisters, model similar mechanisms across the tree of life.  They also propel evolutionary arms races between microbial pathogens and our immune systems, and anti-microbial drugs.

In this course we explore these mechanisms, brainstorm new ideas, chart potential strategies for detecting and preventing pathogenic evolution of resistance, and entertain possibilities outside the box, and outside of outside the box!  The aim will be to develop unconventional, innovative and daring approaches to diagnosing bacterial evolution, and slowing it therapeutically. – Prof. Susan Rosenberg, Director of FEMS Summer School for Postdocs

Mentors and Speakers

Susan M Rosenberg, Ph.D.Susan Rosenberg (Director of FSSfP)  Ben F. Love Chair in Cancer Research,Baylor College of Medicine, Houston, TX USA

Scientific talk(s):
• Stress-induced mutagenesis and antibiotic resistance
• Evolvability protein networks-The DNA damageome

Christophe Herman (Co-director of FSSfP) – Baylor College of Medicine, Houston, TX USA

Scientific talk(s):
• Role of transcription errors in phenotypic plasticity
• Fighting antibiotic resistance by hijacking bacterial functions

Ivan Matic (Co-director of FSSfP) – INSERM, Paris, France

Scientific talk(s):
• Evolution of mutation rates in bacteria
• rRNA operon redundancy as the genome stability insurance

Miroslav Radman (Honorary Director of FSSfP) – FEMS-Lwoff Award winner (2011) for his research of DNA repair mechanism in Deinococcus radiodurans, Co-founder of MedILS

Scientific talk(s):
• On the Biology of Robustness

Daniel JaroszStanford University, Palo Alto, CA, USA

Scientific talk(s):
• High frequency drug tolerance and resistance in pathogenic fungi: A stress-induced interplay of epigenetic and genetic mechanisms
• A stress response that enables hypermutating cells to survive, proliferate, and evolve new traits

Laurence Van MelderenULB, Bruxelles, Belgium

Scientific talk(s):
• Toxin-antitoxin systems: back to the future
• Microbiology goes single cell: from toothpicks to microfluidics and time-lapse microscopy

Pierre Genevaux IBCG, France

Scientific talk(s):
• Toxin-antitoxin-chaperones
• Molecular chaperone evolution

Olivier Tenaillon INSERM, Nice, France

Scientific talk(s):
• Toxin-antitoxin systems: back to the future
• Microbiology goes single cell: from toothpicks to microfluidics and time-lapse microscopy

Aude Bernheim  Weissman Institute, Israel

Scientific talk(s):
• Exploring the diversity of the pan-immune system of bacteria
• From bacteria to human, origin and conservation of immune systems across the tree of life

Josep CasadesusSevilla University, Spain

Scientific talk(s):
• Bistability and phase variation in Salmonella enterica
• Microbiology goes single cell: from toothpicks to microfluidics and time-lapse microscopy

Jade Wang University of Wisconsin at Madison, USA

Scientific talk(s):
• Replication transcription conflicts shape genome organisation
• New insights into alarmones and bacterial stress response

Hilary Lappin-Scott (FEMS President)

Scientific and Professional Development talks:
• Importance of biofilms in resistance and challenges for treatment
• The importance of some of the greater set challenges to early career researchers, including their health and well-being, supporting women and minorities in microbiology

Colin Harwood (FEMS Treasurer) Center for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, UK

Scientific talk(s):
• An interesting aspect of Antibiotic Resistance genes

Patrik Bavoil (FEMS Director of Research and Publications) – Department of Microbial Pathogenesis, University of Maryland Baltimore, USA

Publications talk:
• The FEMS publication portfolio is growing!

The people involved in the organization of the Summer School from the MedILS side are:

  • Dr Branka Bernard
  • Ms Jelena Ruzic
  • Ms Karla Combes
  • Ms Irena Rajic

The people involved in the organization of the Summer School from the FEMS side are:

  • Prof. Vaso Taleski
  • Mr Matthew Harvey
  • Mr Joseph Brooks Shuttleworth

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Featured Issue

Ecology and Physiology of Halophilic Microorganisms

This Thematic Issue of FEMS Microbiology Letters contains eight papers based on oral presentations or posters presented at the 12th International Conference on Halophilic Microorganisms – Halophiles 2019, in Cluj-Napoca, Romania. The location for the event recognizes the great diversity of hypersaline environments in Romania and the rich history of the exploration of the microbial diversity in those environments. This Thematic Issue explores the latest developments on the microorganisms living in these unique environments.

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