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The content of the FEMS Summer School for Postdocs (#FSSfP) will be focused on the following theme:

Microbial Evolvability Mechanisms: Resistance, Biology, and Strategies to Defeat and Detect


Bacteria and phages led the discovery of nearly all basic molecular biological processes for all of life.  More recently, microbes are the vanguard of intriguing new molecular mechanisms that drive evolution and the ability to evolve.  Evolution by variation and selection includes mechanisms of inheritance and creation of variation. These mechanisms, from stress-induced mutagenesis, to RNA- and protein-mediated inheritance, to persisters, model similar mechanisms across the tree of life.  They also propel evolutionary arms races between microbial pathogens and our immune systems, and anti-microbial drugs.

In this course we explore these mechanisms, brainstorm new ideas, chart potential strategies for detecting and preventing pathogenic evolution of resistance, and entertain possibilities outside the box, and outside of outside the box!  The aim will be to develop unconventional, innovative and daring approaches to diagnosing bacterial evolution, and slowing it therapeutically. – Prof. Susan Rosenberg, Director of FEMS Summer School for Postdocs

Directors and Mentors

Susan M Rosenberg, Ph.D.Susan Rosenberg (Director of FSSfP)  Ben F. Love Chair in Cancer Research,Baylor College of Medicine, Houston, TX USA

Scientific talk(s):
• Stress-induced mutagenesis and antibiotic resistance
• Evolvability protein networks-The DNA damageome

Christophe Herman (Co-director of FSSfP) – Baylor College of Medicine, Houston, TX USA

Scientific talk(s):
• Role of transcription errors in phenotypic plasticity
• Fighting antibiotic resistance by hijacking bacterial functions

Ivan Matic (Co-director of FSSfP) – INSERM, Paris, France

Scientific talk(s):
• Evolution of mutation rates in bacteria
• rRNA operon redundancy as the genome stability insurance

Miroslav Radman (Honorary Director of FSSfP) – FEMS-Lwoff Award winner (2011) for his research of DNA repair mechanism in Deinococcus radiodurans, Co-founder of MedILS

Scientific talk:
• On the Biology of Robustness


Mentors and Speakers

Alvaro San Millan, Hospital Universitario Ramon y Cajal, Madrid Spain

Scientific talk(s):
• Evolution of plasmid-mediated antibiotic resistance
• The role of plasmids in bacterial evolution beyond horizontal gene transfer

 Julian Bos, Institute Pasteur Paris, France

Scientific talk:
• Emergence of antibiotic resistance: insights from extracellular vesicles

Daniel JaroszStanford University, Palo Alto, CA, USA

Scientific talk(s):
• High frequency drug tolerance and resistance in pathogenic fungi: A stress-induced interplay of epigenetic and genetic mechanisms
• A stress response that enables hypermutating cells to survive, proliferate, and evolve new traits

Laurence Van MelderenULB, Bruxelles, Belgium

Scientific talk(s):
• Toxin-antitoxin systems: back to the future
• Microbiology goes single cell: from toothpicks to microfluidics and time-lapse microscopy

Olivier Tenaillon INSERM, Nice, France

Scientific talk(s):
• Toxin-antitoxin systems: back to the future
• Microbiology goes single cell: from toothpicks to microfluidics and time-lapse microscopy

Aude Bernheim  Weissman Institute, Israel

Scientific talk(s):
• Exploring the diversity of the pan-immune system of bacteria
• From bacteria to human, origin and conservation of immune systems across the tree of life

Jade Wang University of Wisconsin at Madison, USA

Scientific talk(s):
• Replication transcription conflicts shape genome organisation
• New insights into alarmones and bacterial stress response

FEMS Speakers

Hilary Lappin-Scott (FEMS President)

Scientific and Professional Development talks:
• Importance of biofilms in resistance and challenges for treatment
• The importance of some of the greater set challenges to early career researchers, including their health and well-being, supporting women and minorities in microbiology

Colin Harwood (FEMS Treasurer) Center for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, UK

Scientific talk:
• An interesting aspect of Antibiotic Resistance genes

Patrik Bavoil (FEMS Director of Research and Publications) – Department of Microbial Pathogenesis, University of Maryland Baltimore, USA

Publications talk:
• The FEMS journals and possibility for publication

Vaso Taleski (FEMS Director of Events & Internationalization)

Opening ceremony
• Closing ceremony

The people involved in the organization of the Summer School from the MedILS side are:

  • Dr Branka Bernard
  • Ms Jelena Ruzic
  • Ms Karla Combes
  • Ms Irena Rajic

The people involved in the organization of the Summer School from the FEMS side are:

  • Prof. Vaso Taleski
  • Mr Matthew Harvey
  • Mr Joseph Brooks Shuttleworth

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Featured Issue

C1 Metabolism

Explore a new Thematic Issue on C1 Metabolism from FEMS Microbiology Letters. One-carbon or “C1” metabolism has been studied for many years and in several different forms. This Thematic Issue brings together new research and covers several different subtopics. This issue includes studies on aerobic microorganisms in marine environments, methylotrophic methanogens, hydrogenotrophic methanogens, hemerythrins, methane in forest soils, and methanogenic archaea in peatlands.

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