Volunteer: Goormaghtigh Frédéric
I am a 30-years old post-doc in molecular biology at the Université Libre de Bruxelles (Belgium). During my PhD, I got interested in bacterial persistence, a phenomenon by which very few bacteria transiently operate a phenotypic switch to an antibiotic-tolerant state. I started working on a controversial model in which toxin-antitoxin systems would rule the entry into persistence. We could finally disprove such model after 5 years of intensive research. The question thus remains open: how do some bacteria tolerate extreme doses of antibiotics? We know tackle this question by combining genetics and single-cell microscopy, a very fascinating approach as it allows one to directly observe and analyze how bacteria react to antibiotic treatments. However and because of the long controversy in my field, I understood how important it is to popularize and disseminate the results of scientific research and most importantly to make sure that the information available for non-specialists is of high quality and correct.
FEMS Microbes is excited to present its latest thematic issue, focusing on bacterial-viral co-infections. Host and microbial factors are critically important for influencing the severity and outcome of infection. Interactions between microbes is an understudied yet important aspect to this process.