New Approaches to Combat Antibiotic-Resistant Bacteria
The New Approaches to Combat Antibiotic-Resistant Bacteria research conference bids to review the current knowledge on bacterial physiology in patients; outline the development of relevant in vitro models to study the underlying molecular mechanisms; and provide an overview of novel intervention strategies.
Bacterial infections represent an urgent threat to human health worldwide. Over the past decades, pan-resistant strains of major bacterial pathogens have emerged rendering clinically available antibiotics ineffective. As a result, many achievements of modern medicine are now at risk. New ways to identify clinically effective antimicrobials are urgently needed to counter this threat.
However, the current antimicrobial development pipeline is insufficient because of high attrition and limited coverage of multi-drug resistant Gram-negative bacteria. Among the factors that impact the development of novel antibiotics, our limited understanding of the physiology and heterogeneity of bacterial pathogens in patients ranks highly. Bacteria growing in tissues of patients experience environments that are very different from standard laboratory conditions. Consequently, microbial physiology and population heterogeneity of such target populations greatly differs from bacteria cultures used for antibacterial discovery. Systematic strategies to tackle this fundamental problem are currently missing.
Towards this goal, the meeting unites the world’s foremost scientists in the field of antimicrobial research to win the race against superbugs by bringing together leading clinicians, biologists, engineers and representatives from pharmaceutical companies. This high-profile meeting will introduce students to emerging concepts that promise to accelerate antibacterial discovery, improve treatment regimens and uncover novel targets for eradicating pathogens.
Venue – Monte Verità
Located in Ascona, on the shore of Lake Maggiore in southern Switzerland, Monte Verità is the ideal retreat: a place for reflection and discussion, introspection and creativity, relaxation and activity, surrounded by nature and steeped in history, catering for every need. Monte Verità promotes phyical and mental well-being and is the ideal setting for organizing meetings, developing ideas and holding talks: the place has attracted many writers, intellectuals, artists and political and economic exponents over the years.
Congressi Stefano Franscini in Monte Verità is the meeting platform of the Swiss Federal Institute of Technology of Zürich (ETH-Zürich). It has supported international conferences since 1989.
The nearest international airports are Milan (Malpensa and Linate) and Zürich. The closest train station is in Locarno. Shuttle transfers will be arranged from/to Locarno on June 7th and June 11th
Dan I. Andersson – Uppsala University, SE
Nathalie Balaban – Hebrew University, IL
Priscille Brodin – INSERM Paris, FR
Heike Broetz-Oesterhelt -University of Tübingen, DE
Dirk Bumann – University of Basel, CH
Knut Drescher – Max Planck Institute Marburg, DE
Sophie Helaine – Harvard, US
Deborah T. Hung – Harvard Medical School, US
John McKinney – EPF Lausanne, CH
Christian Lesterlin – CNRS Lyon, FR
Thomas F. Meyer – Max Planck Institute Berlin, DE
Rolf Müller – Helmholz Centre Saarbrücken, DE
Daniel Obrecht – Polyphor, CH
Alexander Persat – EPF Lausanne, CH
Jörn Piel – ETH-Zürich, CH
Laurence Van Melderen – Bruxelles University, BE
Marvin Whiteley – Georgia Institute of Technology, US
Mattia Zampieri – ETH-Zürich, CH
Annelies Zinkernagel – University Hospital Zürich, CH