The Federation of European Microbiological Societies is governed by a Council of Member Society Representatives (Delegates) and a Board of Directors. The FEMS Team runs its operations from Delft, The Netherlands. The FEMS Council meets annually with participants consisting of Delegates from all Member Societies, alongside officers of the Board of Directors. The Council Meetings and the 43rd Annual General Meeting were held in Lisbon, Portugal on 8-9 September 2017.
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) are frequently located on plasmids, which are self-replicating elements of DNA. They are often transmissible between bacteria, and some have spread globally. Novel strategies to combat AMR are needed, and plasmid curing and anti-plasmid approaches could reduce ARG prevalence, and sensitise bacteria to antibiotics. Currently, there is a general lack of in vivo curing options. This review highlights this important shortfall, which if filled could provide a promising mechanism to reduce ARG prevalence in humans and animals. Plasmid curing mechanisms which are not suitable for in vivo use could still prove important for reducing the global burden of AMR, as high levels of ARGs exist in the environment.