PostDoc positions

Postdoc in Microbiome Research: Germany

The following position is available at the department of Microbial Immune Regulation of the Helmholtz Centre for Infection Research (HZI) in Braunschweig: Postdoc in Microbiome Research
The strategic aim of our research group is to discover and characterize how the microbiome influences the hosts susceptibility to infectious diseases and inflammation in both mouse models and humans. In order to understand how the microbiota influences the host, we have applied an interdisciplinary combination of sequencing-driven, microbiological and immunological approaches to gnotobiotic mouse models and patient cohort (e.g. Thiemann et al., Cell Host Microbe 2017; Roy et al, Cell Reports 2017; Alpizar-Rodriguez D, et al., Ann Rheum Dis. 2019). To strengthen our team, we are looking for highly motivated candidates interested to study the interplay of microbiota and the host. The successful candidate will be responsible to study the effect of distinct commensal bacteria and communities on the host immune system and identify the consequences on diverse diseases models using a combination of cultivation-based, immunological, or bioinformatical approaches.
Activities and responsibilities
For microbiologists, immunologists, or related expertise:
  • Experience in the field of microbiome research (cultivation, characterization)
  • Experience in mouse models of arthritis or IBD research
  • Familiarity with genetic modification of bacteria and / or immune cells (e.g. conjugation, lentiviral or CRISPR/Cas9).

For bioinformaticians:

Knowledge of using high performance computing clusters and programming skills (R, Python, …)

  • Experience in handling multi-omics data, including metabolomics and proteomics
  • Ability to develop statistically supported methods of multi-omics data analysis

Qualification profile

  • We are looking for a highly motivated, creative and enthusiastic individual, who is able to do research independently as well as part of an interdisciplinary and international team.
  • Candidates should hold a PhD or equivalent in Microbiology, Immunology, or a related experimental life sciences field or Bioinformatics.
  • Experience with either: in vitro and in vivo mdels for infection and inflammation research r analysis f NGS sequencing data (e.g. transcriptome, metagenome, or scRNAseq).
  • Strong record of publication in peer-reviewed journals.
  • Excellent communication skills and proficiency in English


The HZI provides modern laboratories, state-of-the-art facilities for immunology and microbiome research including a germ-free mouse facility, anaerobic chambers, and a wide-range of NGS platforms, a large computing cluster, a lively scientific community and excellent support for the development of personal soft-skills that will provide the ideal background to further develop the career of successful candidates.
Equally well-qualified disabled applicants will be given preference. Equal opportunities are part of our personnel policy. The position is suitable on part-time employment.

Starting date: September 1st, 2019 (or later) – 3 years – Salary: TVöD E13 Probation period: 6 months Closing date: 21.04.2019

Further details
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