University of Oxford is seeking to appoint a Research Assistant to join Professor Rob Klose’s research group  which studies how chromatin-based processes at CpG islands regulate gene expression. The Klose lab extensively use model cell culture systems and CRISPR/Cas9-based genome engineering to study how these systems function in normal biology and human disease. You will be responsible for working closely with other lab members to plan, generate, and validate new cell culture models using CRISPR/Cas9-based genome engineering as part of ongoing projects in the lab.

The applicant

• should possess a BSc or MSc in a relevant subject area.
• will have a strong background in mammalian cell culture and a keen interest in chromatin biology and gene expression.
• must be able to work both independently and as part of a research team, and have exceptional organisational, communication, and multitasking skills. The ability to manage your own research and administrative activities is also essential.
•  ideally would have experience in: mouse embryonic stem cell culture, molecular cloning, protein analysis, and PCR-based analysis of DNA and RNA.

This full-time fixed-term post is funded by the Wellcome Trust for up to 1 year in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford.