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Research Fellow- host-microbiota interactions: UK

Queen’s University Belfast is one of the leading universities in the UK and Ireland, with a distinguished heritage and history. With over 24,000 students, 3,700 staff and an annual turnover of some £300m, Queen’s University Belfast plays a unique leadership role in Northern Ireland. As a member of the Russell Group of UK research-intensive universities, Queen’s University Belfast combines excellence in research and education with a student centred ethos. The Centre for Experimental Medicine is an interdisciplinary research centre which is committed to the highest quality scientific endeavour, with over 250 basic and clinical scientists working on site. Our mission is to understand the mechanisms of disease and use that understanding to develop innovative new treatments and therapies to improve patient outcomes. We are based in Belfast in the award winning Wellcome-Wolfson Institute for Experimental Medicine.

This 2 year postdoctoral position seeks an enthusiastic, ambitious and productive individual to join the highly collaborative Mucosal Immunometabolism & Microbial Symbiosis research team led by Dr Eric Campbell in the Wellcome-Wolfson Institute for Experimental Medicine. The position will involve working on elucidating the influence of mucosal metabolism on host-microbiota interactions in the gut, with a view to characterising dysbiosis in disease states and promoting restoration of host-microbial symbiosis. The project is at the interface of microbiology, mucosal immunology and stem cell differentiation and will utilise cutting-edge in vitro, ex vivo and in vivo models of infection and inflammation.

Candidates should have a strong research background in Immunology, Microbiology, Developmental/Stem cell biology or a related discipline. The post is a senior role in the team and as such, successful applicants will have responsibilities in independent research, supervision, planning, day-to-day lab management, collaborations and outreach. The post is suited to a highly ambitious individual, preferably with previous postdoctoral experience, and is available for 2 years.

The successful Research Fellow will have:

  • have or about to obtain a PhD in Immunology, Stem cell/Developmental Biology, Microbiology, or a closely related area
  • at least 3 years recent relevant research experience in immunology, stem cell/developmental biology, molecular/cellular microbiology or relevant discipline
  • recent extensive hands-on experience in at least six of the following areas: – primary cell isolation and culture. – organoids/enteroids/iPSC/MSC culture – microinjection and/or micromanipulation – In vivo mouse models of disease (gut, lung, CNS or cancer/xenograft models) – CRISPR gene editing – molecular biology techniques (Single cell transcriptomics, RNA-seq, ChIP, cloning etc.) – multi-colour flow cytometry, characterization of immune cells (or FACS) – molecular bacteriology (generating bacterial mutants) – confocal microscopy – immunohistochemistry or in-situ hybridization

For full criteria and to apply online, visit www.qub.ac.uk/jobs. You must clearly demonstrate how you are meeting the criteria on your application. For further information or assistance contact Resourcing Team, Queen’s University Belfast, BT7 1NN. Telephone (028) 9097 3044 or email on resourcing@qub.ac.uk

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