American Academy of Microbiology
The American Academy of Microbiology is the honorific leadership group within the American Society for Microbiology (ASM), the world’s largest life science organization. The Academy aims to recognize scientists for outstanding contributions to microbiology and provide microbiological expertise in the service of science and the public.
The investigation of novel approaches for tackling the antimicrobial resistance crisis must be part of any global response to this problem if an untimely reversion to the pre-penicillin era of medicine is to be avoided. One such promising avenue of research involves so-called antibiotic resistance breakers (ARBs), capable of re-sensitising resistant bacteria to antibiotics. This review introduces the area of ARB research, summarises the current state of ARB development with emphasis on the various major classes of ARBs currently being investigated and their modes of action, and offers a perspective on the future direction of the field.