EMBO | EMBL Symposium Mechanisms of drug resistance and tolerance in bacteria, fungi, and cancer

Date: 18 – 21 Mar 2025
Abstract submission deadline: 12 Jan 2025
Location: EMBL Heidelberg and Virtual
Link: https://www.embl.org/about/info/course-and-conference-office/events/ees25-01/

Symposium overview

Resilience to antimicrobial drugs is a rapidly increasing problem of global health. Similarly, cancer cells that become drug-resistant or tolerant affect therapy outcomes, for instance during cancer chemotherapy. The underlying biological mechanisms of tolerance, resistance, and persistence are increasingly being studied and reveal a complex interplay between (cellular) evolution, biochemistry, and metabolism. Understanding these mechanisms holds the long-term promise of developing new therapeutic strategies less prone to drug resistance and, in the short term, enhances our understanding of clonal evolution and single-cell biology. With this new symposium, we aim to gather a highly international group of researchers to exchange in-person on the latest work on the biological mechanisms that mediate drug resistance and tolerance across the species barriers.