INTERNATIONAL COURSE ON ANTIBIOTICS AND RESISTANCE (ICARE)
This course, organized by Institut Pasteur, is designed for early career scientists – assistant professors, new industry scientists, MDs, and postdoctoral research associates – as well as members from developing areas contending with the practical challenge of managing the antibiotic resistance problem with limited resources. Attendance will be limited to 40 students and will reflect the global nature of the problem.
The faculty is composed of 40 internationally recognized scientists and physicians who have made important contributions to antibiotic development, and infectious diseases and resistance management. Faculty will be in residence for a minimum of two days and accessible for informal interactions. Graduates will emerge with a state-of-the-art understanding of existing antibiotics: modes of action, pharmacology, toxicology, mechanisms of resistance, impact of antibiotics on human and other ecologies, current approaches for mining chemical space for antimicrobial activity, the process of advancing hits to leads, the application of next generation nucleic acid-based technologies for antibiotic discovery and resistance detection, and perhaps, most importantly, training and experience in thinking creatively and innovatively about solutions to the problem. The course aims to build an international cadre of collaborative, well networked, and highly trained specialists.
THE THEMES OF THE CONFERENCES
Current infectious disease management and antibiotic use
Modes of action and mechanisms of resistance of existing classes : Cell wall, Ribosome, Nucleic acid synthesis / replication / transcription, Efflux
Origin, mutations, and identifications of antibiotic resistance mechanisms
Antibiotic chemical matter : Natural products, synthetics
Antibiotic development and approval
New topics in antibiotic discovery
Strategies for more focused applications of antibiotics
New technologies for determination of susceptibility and detection of resistance
New antiinfective strategies
THE THEMES OF THE PRACTICAL WORK
Choosing the DNA sequencing technology
Data bases for antibiotic resistance and virulence
Detection and identification of resistance genes
Mobile genetic elements
The course will be administered over 8 days and will consist of formal instruction, review of the literature, small group problem solving including hands-on use of relevant computational tools, innovation-driven brainstorming sessions, and network building.
Place: Les Pensières, Annecy, France
Dates: 6-14 October 2018
Application deadline: 15 May 2018
Diploma: Institut Pasteur Diploma