Multiple PhD positions at University Medical Centre Hamburg-Eppendorf: Germany

Multiple PhD positions are now advertised at University Medical Centre Hamburg-Eppendorf (UKE – Universitätsklinikum Hamburg-Eppendorf) in Germany. The UKE is a pulsating centre of health in the heart of Hamburg. When you are surrounded by that much energy and when progress sets the pace, no two days are the same. More than 14,100 employees with very different responsibilities are united by the same goal: ensuring health and well-being.


  1. PhD 1 (Prof. Aepfelbacher): The mechanisms by which enteropathogenic bacteria of the genus Yersinia reprogram cells of the innate immune system are investigated using a variety of methods, e.g. high-resolution fluorescence microscopy, CRISPR/Cas-mediated genetic engineering, and proteome and genome analyses.
  2. PhD 2 (Prof. Fischer): How chronic DNA viruses modulate host cell responses to establish infection is studied using genome-wide high-throughput sequencing methods. We are using omics technologies to study host response and chromatin changes in DNA virus infection and pathogenesis.
  3. PhD 3 (Dr. Pfefferle/ Dr. Lütgehetmann): To characterize pathomechanisms and tropism of different SARS-CoV-2 variants, infection models and reverse genetics are used and virological analyses of human tissue samples are performed for evaluation. In addition to work under the S3 safety level (viral culture, viral quantification), a variety of molecular (cloning, mutagenesis, qPCR and sequencing) and imaging (immunofluorescence, ISH) techniques will be used.

We are looking forward to

  • Degree in natural sciences (biology, biochemistry, molecular life science, pharmacy, or similar)
  • Ideally practical experience in molecular biological methods and immunological techniques
  • Conscientious and structured work
  • Commitment, team and communication skills, independence and flexibility
  • Competent language abilities in English

What we can offer

  • Regular payment according to German Public Services Regulations TVöD/VKA; attractive company pension plan and various employee discounts
  • 30 days vacation; possibility of special leave and sabbatical
  • Central location: Our clinic is centrally located at the beautiful Eppendorfer Park
  • Sustainable travel: subsidies for the HVV-ProfiTicket and Dr. Bike bicycle service; option of leasing a company bicycle
  • Crisis-proof workplace, meaningful activity, appreciative interaction and open exchange of knowledge within the team; structured induction training
  • Opportunity to actively shape and develop your working environment as part of our employee program (UKE INside)
  • Extensive continuing education programs (UKE Academy)
  • Family-friendly working environment: cooperation for childcare, free vacation care, advice for employees with relatives in need of care
  • Excellent health, prevention and sports offers
  • Healthy and varied lunch break: in addition to our canteen, there is a rich selection of culinary offerings just a few steps away, for example the “Health Kitchen” cafés and bistros, as well as other snack bars, bakerys, a supermarket, etc.

More information

Your contact to Recruiting: You can reach us by phone: (040) 7410-52599 or by e-mail:

Your contact to the department: Dr. Katja Giersch, by e-mail:; Dr. Marc Lütgehetmann:


Please note that your application can only be considered if you are fully immunised against the SARS-CoV-2 virus (at the latest at the start of engagement), supported by valid official vaccination certificate(s). Please submit these with your application.

We offer a work environment providing equal opportunities regardless of age, gender, sexual identity, disability, origin or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disability with equal aptitude, competence and professional performance will be given priority.

We look forward to receiving your completed application by May 2nd 2022 stating reference code 22327_eng.

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