Dr. Aneesh Thakur, Principal Investigator, Laboratory of Vaccine Engineering, and Immunology (LVEI) is seeking an outstanding Postdoctoral Fellow focusing on Tuberculosis (TB) vaccine development to join his team.

Mycobacterium tuberculosis, the causative agent of TB, enter the human body via the airways. One possible strategy to generate protective immunity in the lungs against TB is by vaccination in the respiratory tract. However, little is known about how to design safe TB vaccines for administration in the respiratory tract and how to achieve potent airway mucosal immunity against TB. The purpose of this project is to elucidate the essential design criteria for inducing protective pulmonary immunity by TB vaccines and identify mucosal immune correlates of protection. The project will combine approaches in immunology, bacteriology, formulation, and in vivo infection models to achieve the objectives.