Postdoctoral fellow in computational cancer genomics: Sweden
The University of Gothenburg tackles society’s challenges with diverse knowledge. 38 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.
The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.
The Institute is composed of the following five departments:
• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Pathology and Genetics
• The Department of Clinical Chemistry and Transfusion Medicine
• The Department of Medical Biochemistry and Cell Biology
At present, the institute has about 360 employees and approximately 400 million SEK in total assets.
Subject area description
Tumor development involves somatic alterations in cellular DNA, typically in protein-coding genomic regions. We are interested in how mutations and other chromosomal changes arise and distribute across tumor genomes and how they contribute to cancer, in both protein coding and non-coding DNA. For these studies we make use of publicly available as well as in-house generated high-throughput datasets.
The project will involve bioinformatical analysis and integration of large-scale genomic data from tumors, including relevant public datasets. The emphasis will be on biological questions rather than bioinformatics methods. The work will be carried out in collaboration with experimental scientists. Relevant recent publications from our group include: Fredriksson et al., Plos Genetics 2017; Alaei-Mahabadi et al., PNAS 2017; Stewart et al., Plos Genetics 2015; Fredriksson et al., Nature Genetics 2014; Tang K-W et al., Nature Communications 2013.
An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.
The qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.
Programming skills and linux/unix experience is a requirement, and knowledge of Matlab or R is desired. Previous experience with next-generation sequencing is recommended. Experience from relevant biological fields is desirable, and the applicant is expected to have published several articles in peer-reviewed journals. Excellent communicative skills are required, including fluency in oral and written English.
Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.