We (Laboratory for Cellular Metabolism and Metabolic Regulation; Fendt Lab) are a young and dynamic team of researchers performing cutting edge cancer metabolism research with special focus on cancer metastasis and novel metabolic pathways. We exploit in vivo mouse models, metabolomics and 13C tracer analysis to gain groundbreaking insights into metabolism as a driving force of cancer progression. Our work is published in high profile journals such as Nature, Nature Communications, Cell Reports, and Nature Immunology. We have a strong international recognition and top collaboration partners all over the world.

The VIB-KULeuven Center for Cancer Biology (CCB), located on the Campus Gasthuisberg of the University of Leuven, contributes to the better understanding of the biology that underlies cancer initiation, progression and metastatic dissemination with the ultimate goal to develop more effective and specific anti-cancer (combination) therapies. CCB is currently composed of more than 200 scientists in 12 independent research groups and units. Our scientific interest lies in various hallmarks of tumors and their microenvironment, including inflammation, metabolism, genetic and epigenetic regulating circuits. CCB fosters an interdisciplinary environment and close collaboration with the Comprehensive Cancer Center LKI and the University Hospital, both located on the same campus, to promote translational research.

VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on groundbreaking research in life sciences. About 1500 scientists and technologists from over 60 countries are based at the 5 Flemish Universities of Ghent, Leuven, Antwerp, Brussels and Hasselt, and are studying the broad spectrum of molecular mechanisms that regulate the functions of the human body, plants and microorganisms.

Profile

Are you interested in cancer metabolism and signaling pathways? You have a strong background (PhD) in cell signaling. You bring a strong expertise in dissecting signaling cascades (a background on mTOR is a plus), you have successfully applied state-of-the-art genetic engineering technologies (such as CRISPR/CAS9), and you are an expert in molecular biology techniques including but not limited to western blot, qPCR, FACS, immunohistochemistry (IHC), and cell culture techniques. Expertise in mouse models, cancer, the tumor microenvironment, and/or immunology is a plus. You are interested in metabolism research. You like taking the scientific and experimental lead on a challenging project. You can work independently but also like to collaborate within the team and other research groups. You aim for high impact.

We offer

• cutting edge research projects funded by the European Research Council (ERC)
• the opportunity to lead exciting research projects in metastasis formation and novel metabolic pathways
• multidisciplinary and international collaborations
• beyond state-of-the-art technologies including mass spectrometry and single cell RNAseq
• team work and individual research career development
• international team of young and dynamic researchers

How to apply?
Please apply online: motivation letter, full CV, list of publications and contact details of 4 referees in one single pdf file

Deadline to apply: January 15, 2018.

For more information: Please contact us (https://www.vibcancer.be/sarah-maria-fendt) or follow us on Twitter (@FendtLab)