The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) in close collaboration with the RIKEN Center for Integrative Medical Sciences (Japan): Postdoctoral researcher in Human Microbiome-Immune System Interactions (m/f)

Position is suited for:

• a highly motivated and creative scientist with a highly successful record in scientific research who can independently design and execute experiments.
• an individual with a strong interest in fundamental and translational aspects of host immunity and its relation with the gut microbiome using state-of-the-art approaches that combine immunology, cell biology, biochemistry and animal models of infection.

The project also involves a newly developed microfluidics-based model of the gastrointestinal human-microbe interface, called HuMiX, which allows proximal co-culture of human epithelial and immune cells together with gut microbes under physiologically representative conditions.

Your Role

• Conceptualisation and design of experiments using the HuMiX model for the concomitant cultivation of human and microbial cells.
• Cultivation of human cell lines, microbial communities and immune populations with a particular focus on adaptive immune cell populations, including Treg and CD8 T cells.
• Performing experiments in germ-free and gnotobiotic mouse models of barrier dysfunction.
• Generation and analysis of readouts including multicolor FACS, CyToF, animal models and molecular biology techniques.

Your Profile

• A PhD in Immunology, Cell Biology or Microbiology.
• Strong publications record.
• Training in immunological methods especially multicolor FACS.
• Training in molecular biology, microbiology and cell culture techniques.
• Interest in T cell biology.
• Previous experience in microbiology and experience in handling mice will be considered an asset.
• Excellent working knowledge of English.

For further information, please contact:
Prof. Dr Paul Wilmes
E-mail: paul.wilmes@uni.lu