Postdoctoral Researcher in metabolomics: France
The French School of Public Health, a member of the Research Institute for Environmental and Occupational Health seeks highly qualified candidates for a postdoctoral research position to work in the field of metabolomics. The successful candidate will be responsible for developing a high throughput metabolomics-based analytical method using UHPLC-ESI-Q-TOF in order to screen xenobiotics in NCI-H295R cell lines and study how these xenobiotics are disrupting major biological pathways at the metabolome level. Specific duties include developing new sample preparation methods for separating steroids and other metabolites in NCI-H295R culture medium, be involved in the optimization of in vitro assays to obtain the best analytical sensitivity, process data from xenobiotic screening using vendor software for targeted analyses and open-source software for untargeted analyses.
We seek a highly motivated and enthusiastic candidate with a PhD in the area of metabolomics, or analytical chemistry with experience. The successful applicant will work at the Laboratory for Research and Study in Environment and Health (LERES), a major analytical platform fully integrated within IRSET-Inserm U1085. Essential skills for this job include experience in biological sample preparation techniques, strong practical expertise in liquid chromatographic methods, LC-HRMS based metabolomics and experience in metabolite deconvolution software and Mass Spectral Database.