A post-doctoral position is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France. Our team investigates the mechanisms of cell proliferation and cell-cell communication using fission yeast as a model system, taking advantage of multidisciplinary approaches including synthetic biology, high-resolution live-cell imaging, microfluidics, and experimental evolution (for more information, see www.synthecell.org). The proposed project aims at understanding the interplay between the dynamics of the cell cycle oscillator and cellular behavior, in particular in the context of networks of communicating cells.

We are seeking a motivated candidate to take on this exciting project in a collegial, interactive and international environment. Candidates with a background in yeast genetics as well as molecular and cell biology are encouraged to apply. Experience with microscopy, image analysis and microfluidics will be particularly useful for this project.

Relevant references:

Chen T, Gomez-Escoda B, Munoz-Garcia J, Babic J, Griscom L, Wu PY, Coudreuse D. A drug-compatible and temperature-controlled microfluidic device for live-cell imaging. Open Biology (2016) 6:160156.

Banyai G, Baïdi F, Coudreuse D* and Szilagyi Z. Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription. Nature Communications (2016) 7:11161. *Co-senior and corresponding author

Gérard C, Tyson JJ, Coudreuse D*, Novak B. Cell cycle control by a minimal Cdk network. PLoS Comput Biol (2015) 11(2):e1004056. *Co-senior and corresponding author

Coudreuse D* and Nurse P. Driving the cell cycle with a minimal CDK control network. Nature (2010) 468:1074-9. *Corresponding author

Research at the Institute of Genetics and Development of Rennes covers a wide range of subjects in cell biology, taking advantage of most classical model systems while strongly promoting interdisciplinary approaches. The IGDR is dynamic and expanding, with 21 teams representing 200 international researchers and staff, including several recently established young groups. The working language of the laboratory and the institute is English.

The IGDR is located in the city of Rennes, the capital of Brittany in northwestern France. With its rich tradition of cultural, musical, and artistic events as well as its close proximity to the coast, Rennes is a very welcoming and pleasant place to live. It is also easily and directly accessible from Paris (around 1h30 by train).

How to apply:

Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send 1) a Curriculum Vitae, including past research experiences and publication records, 2) a letter detailing their motivation, interest in our work and career plans, and 3) a copy of their PhD diploma. All documents must be copied to recherche@u-bretagneloire.fr.

Applicants should also request recommendation letters to be directly sent to Dr. Damien Coudreuse by at least two references.

This project is co-funded by the Region Bretagne and the Universite Bretagne Loire.