Pathogens and Disease Poster Prize: Francis Cavallo
The FEMS Conference on Microbiology (#FCOM22) took place on the 30th June until the 2nd July in Belgrade, Serbia. With 450 posters on display the Pathogens and Disease editorial board selected Francis poster on bacterial resistance to predation by Bdellovibrio bacteriovorus as the best poster.
Read our interview with Francis about his research below:
What is your current position, and what was your scientific journey to get there?
My research focused on understanding antibiotic resistance, with particular focus on bacterial predators and their uses. My academic career started with a Bachelor’s in Biotechnology from the small Italian University of Potenza, followed by a Master’s at the Royal Institute of Technology in Stockholm, Sweden. I recently completed my education by earning my Ph.D. in Microbiology at the University of Groningen.”
Could you describe the research your poster covered?
My poster investigated possible factors that determine bacterial resistance to predation by Bdellovibrio bacteriovorus, a bacterial predator which preys upon other Gram-negative bacteria. The study investigated the involvement of core Lipopolysaccharides (LPS) of Escherichia coli prey. In the present context of rising antibiotic resistance to conventional chemical antibiotics, the natural ‘antibiotic’ characteristics and molecules from organisms such as B. bacteriovorus could be exploited for the research of new and alternative antimicrobial molecules.”
What do you hope to focus your research on in the future?
I would like to keep investigating the mechanisms that allow bacteria to acquire resistance. In my opinion antibiotic research needs to shift from purely chemical solutions to more biological ones. Taking advantage of ‘alive’ antibiotics that evolve and adapt to the prey that they target constitutes a cutting edge in favor of natural antibiotics.”
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FEMS Yeast Research is proud to present this latest thematic issue on yeast pathogenesis and drug resistance. In the past few decades, genetics and genomics studies have uncovered traits underlying the pathogenicity and drug resistances of pathogenic yeast. However, we still have a lot to uncover about the complex mechanisms used by different species to thrive in the human host, and much to do to convert this knowledge into improved clinical treatments. This thematic issue highlights the importance of the diversity of genome-scale approaches to unravel the intricate nature of pathogenesis and drug resistance in pathogenic yeasts, bringing together a diverse range of fascinating views on antifungal drug resistance.