Projects

Our projects challenge important issues in microbiology and advocate an open and honest discussion from the microbiology community. Find out how you can get involved, read our latest news, and discover why these issues matter.

Increasing Project Impact – we invite proposals from organizations who seek a wider promotion and increased the impact of their activities
Peer Review – emphasizes and celebrates the fundamental role that peer review plays in the scholarly communications landscape
One Health – shows the biggest achievements of the One Health concept and how it facilitates interdisciplinary collaboration into actual science and policy
Fighting AMR – helping you find antibiotic solutions to tackle antimicrobial resistance (AMR) and address this challenge globally
Featured article

Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing

Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) are frequently located on plasmids, which are self-replicating elements of DNA. They are often transmissible between bacteria, and some have spread globally. Novel strategies to combat AMR are needed, and plasmid curing and anti-plasmid approaches could reduce ARG prevalence, and sensitise bacteria to antibiotics. Currently, there is a general lack of in vivo curing options. This review highlights this important shortfall, which if filled could provide a promising mechanism to reduce ARG prevalence in humans and animals. Plasmid curing mechanisms which are not suitable for in vivo use could still prove important for reducing the global burden of AMR, as high levels of ARGs exist in the environment.

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