Prof Ulrich Dobrindt
Head of the Section 'Microbial Genome Plasticity', Institute of Hygiene, University of Münster
- Bacterial genome plasticity, evolution and adaptation
- Comparative and functional genomics
- Host-bacterium interaction
FEMS Expert: Prof Ulrich Dobrindt
Prof Ulrich Dobrindt studied biology at the University of Göttingen, Germany and graduated at the University of Würzburg in 1999. Since 2010 he has been Professor at the University of Münster, Germany.
The Dobrindt group works on fundamental and applied research questions related to the geno- and phenotypic variability of bacterial pathogens, which can cause disease in humans and animals. Using Escherichia coli as a model, they want to understand the underlying mechanisms for infection.
Commensal and pathogenic bacteria interact in different ways with host barriers. Dobrindt’s laboratory aims to identify bacterial properties and the molecular mechanisms involved in host-bacterium interaction. To correlate genomic plasticity with bacterial fitness or virulence, they investigate the bacterium-host interaction at cellular barriers, genome-scale evolution and adaptation of E. coli and E. coli factors involved in metabolic adaptation to different host niches.
Another research focus is on the characterization of microbial genome plasticity and its impact on the evolution and spread of antibiotic resistances as well as on novel strategies, e.g. bacterial interference or photosensitizers, to combat bacterial infection.