Partnering with FEMS
FEMS is a unique, active and diverse network of around 30,000 professionals who are committed to advancing microbiology for the benefit of society in the areas of health, energy, food, materials and the environment. Set up in the UK as a small charity in 1974, today we are a growing coalition of over 50 Member Societies from 38 countries across Europe. Many of those in our network are early career researchers. Others are experienced scientists, industry professionals, students and campaigners.
The investigation of novel approaches for tackling the antimicrobial resistance crisis must be part of any global response to this problem if an untimely reversion to the pre-penicillin era of medicine is to be avoided. One such promising avenue of research involves so-called antibiotic resistance breakers (ARBs), capable of re-sensitising resistant bacteria to antibiotics. This review introduces the area of ARB research, summarises the current state of ARB development with emphasis on the various major classes of ARBs currently being investigated and their modes of action, and offers a perspective on the future direction of the field.