Out of the FEMS Research and Training Grantees, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) annually selects one grantee for an additional award of € 1000, the FEMS-ESCMID Awardee. Reciprocally, FEMS will provide such additional award to one grantee, the ESCMID-FEMS Awardee. These joint fellowships will receive appropriate publicity through both organizations.
The aim of this study was to determine whether in vitro induced erythromycin resistance facilitates the cross-resistance to the novel fluoroketolide, solithromycin, in Staphylococcus aureus. Long-term exposure of erythromycin results in resistance to ketolides in S. aureus through drug binding site mutations. These results demonstrate that since erythromycin has been used clinically for a long time, it is necessary to carefully evaluate the rewards and risks when prescribing solithromycin for the treatment of infectious diseases.